Abstract: The rise of agentic AI has catalyzed a shift toward self-iterating systems, opening new frontiers for the autonomous optimization of production recommender models. This paper presents the empirical validation of a knowledge-driven autonomous agent system, deployed directly on a production large-scale Two-Tower retrieval model. By delegating the entire research lifecycle, spanning idea generation, code implementation, offline training, and metric evaluation, to a continuous closed-loop autonomous framework, the agent system executed over 40 completed autonomous training runs from scratch. Executing these runs under rigorous production-scale evaluations, the system systematically navigated hidden architectural bottlenecks on the latest production model to achieve a breakthrough ~20% relative improvement in NDCG, a gain that translated directly to a +3.77% increase in user satisfaction in live production traffic. Furthermore, the deployment exposed critical vulnerabilities in standard evaluation protocols, as the agent system autonomously discovered reward-hacking shortcuts. These findings prove that an autonomous pipeline can dramatically accelerate the pace of machine learning research and stress-test the rigorousness of underlying experimental infrastructure, while also exposing novel challenges such as reward hacking and redundant exploration of failed hypotheses.
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