Abstract: Fatigue, sleep, or disturbances in daily activities are common symptoms among patients with neurodegenerative disorders (NDD) and immune-mediated inflammatory diseases (IMID). The current assessment of such symptoms is usually conducted using patient reported outcomes (PROs) based on standardized questionnaires that patients usually complete every few months. This assessment protocol has raised some concerns, due to its propensity to exhibit biases derived from its subjectivity nature, or the low sensibility to changes, which may lead to a failure when trying to capture variability over time. In this work, we explore the use of smartphone data, which can serve as a proxy for how patients interact with their devices, to provide an effective, reliable, and objective assessment of the symptoms mentioned above. Our study comprises data from 137 participants belonging to 6 different disease groups, plus a healthy control group. We conducted statistical analysis based on repeated measures correlation, in which we analyze the correlation between screen-time and app-usage features with scores obtained from the PROs collected from the participants using a smartphone application.
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