arXiv:2609.38559v1 Announce Type: new
Abstract: This paper examines human-AI interactions (HAIIs) in clinical trials and presents a multidimensional categorisation framework that classifies interactions according to AI tasks, human-AI relationships, interaction configurations and interacting human groups. We define HAII, examine existing taxonomies and extend existing categorisation approaches through this novel multidimensional framework. We purposively sampled 15 clinical trials from a previously reported dataset. Each trial was independently categorised by two human reviewers and six large language model (LLM) classifiers. The proposed categorisation provides a structured method for the consistent identification, comparison and synthesis of human-AI interactions across clinical-trial records. The framework is intended to support more consistent comparison and synthesis of AI-related clinical trials and to make explicit the different forms of human involvement associated with AI interventions. The results demonstrate the potential for LLM-assisted categorisation while indicating the continuing importance of human judgement where trial records are incomplete or ambiguous. The principal contribution is a proposed multidimensional framework that brings together AI tasks, human-AI relationships, interaction configurations and interacting human groups within a single approach designed for clinical-trial records. Its significance lies in its potential to support more systematic identification, comparison and synthesis of how humans and AI interact in clinical trials.
Abstract: This paper examines human-AI interactions (HAIIs) in clinical trials and presents a multidimensional categorisation framework that classifies interactions according to AI tasks, human-AI relationships, interaction configurations and interacting human groups. We define HAII, examine existing taxonomies and extend existing categorisation approaches through this novel multidimensional framework. We purposively sampled 15 clinical trials from a previously reported dataset. Each trial was independently categorised by two human reviewers and six large language model (LLM) classifiers. The proposed categorisation provides a structured method for the consistent identification, comparison and synthesis of human-AI interactions across clinical-trial records. The framework is intended to support more consistent comparison and synthesis of AI-related clinical trials and to make explicit the different forms of human involvement associated with AI interventions. The results demonstrate the potential for LLM-assisted categorisation while indicating the continuing importance of human judgement where trial records are incomplete or ambiguous. The principal contribution is a proposed multidimensional framework that brings together AI tasks, human-AI relationships, interaction configurations and interacting human groups within a single approach designed for clinical-trial records. Its significance lies in its potential to support more systematic identification, comparison and synthesis of how humans and AI interact in clinical trials.
This article has been indexed from cs.AI updates on arXiv.org
Read the original article: