Abstract: Groundwater variability in Ghana remains poorly characterized due to limited long-term in-situ observations. This study investigates groundwater storage anomalies using GRACE-derived data from 2004-2024 combined with statistical analysis and unsupervised machine learning. Groundwater anomalies were standardized using Z-scores, while an ensemble-based Isolation Forest framework was applied for anomaly detection. The results revealed substantial temporal variability, with persistent groundwater deficits during 2004-2009 followed by increasing positive anomalies after 2018. A total of 12 anomalous months were identified, comprising 5 deficit and 7 surplus events, with the strongest anomalies associated with groundwater deficits. Spatial analysis showed more frequent deficit anomalies in northern Ghana and stronger surplus occurrence in southern regions. Comparison with statistical thresholds further indicated that the machine learning framework captured additional subtle deviations beyond conventional threshold-based methods. Overall, the integration of GRACE observations with unsupervised anomaly detection provides a practical framework for groundwater monitoring in data-scarce environments.
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