Abstract: Reliable and low-latency communication is a fundamental requirement for smart city services and Industry 4.0 applications enabled by NR-V2X networks. However, limited Road-Side Unit (RSU) deployment and complex urban propagation conditions often prevent Connected and Automated Vehicles (CAVs) from maintaining stable connectivity. This paper proposes an AI-driven Learning-to-Optimise (L2O) framework based on Graph Neural Networks (GNNs) for real-time multi-hop relay selection in NR-V2X systems. The vehicular network is modelled as a graph, where nodes represent CAVs and RSUs, and edges encode radio-link characteristics. An offline Mixed-Integer Linear Programming (MILP) formulation provides optimal relay decisions used as supervision for training an edge-aware Graph Isomorphism Network with Edge Features (GINE). Extensive experiments on realistic urban datasets demonstrate that the proposed approach achieves near-optimal connectivity performance, recovering up to 11.3% connectivity gain, while reducing execution time by orders of magnitude (up to 100 x speed-up) compared to MILP. The framework enables scalable and real-time network control, making it suitable for smart city and Industry 4.0 deployments.
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